Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length510 amino acids

Chemical FormulaC2473H3911N657O760S20

DescriptionStandard

        MQTGQNQTTASSFSHRHKQSAGGDGVLLDVCEFHFSVTQEIKAERQHREAEATCLHTQSNSEELNLASSSRISAEENASICDSSARPPLLRLWRKSCSASCPDQQGASVRITIVKCDLPEPSVEFLQNPPGFQTTISDLSIAITGDWRTHFGLIHDGGTFDMAIYNVDVTSVAQLGKEADGHPSVSSLSCHSQVGDVDIEFHGGASFIFQPFVKHFKGRIRDEIQKRLCPGVEGNIQSFEDHLHVMNVSVDVNEVLTLALPLTDVPIIGASGMNVGLKGEFYNIKTPVEPPFEAQPFTMPDEPSYMLSVGMSDFTLNSASYAYFSAKLLQLLITDSMIPPISPVHLNTTSLGKFIPKLAEMYPDMLMSVLVYAQEAPKFSIQPDAINVSIKAVAKASVILPNGTQIPVFTINVDSKFSSELWIDDGKLKGSVKMDNVTLTLASSEVGTFKTDSLESLARTGGKFVLVKVNQKLREGFLVLRTKYAQLVNSVLKKEKGFLSISSDVQVVLT
    

Molecular Weight55647.75 Da

Isoelectric Point (pI)5.56

Net Charge (pH 7.0)-12.28

Net Charge (pH 7.4) -13.45

Charge Density (pH 7.0) -0.0241

GRAVY Index-0.07

Hydrophobic Moment 0.68

Boman Index0.08

Instability Index43.38

Aliphatic Index 89.61

Aromaticity 0.0725

Extinction Coeff. Reduced 28420.00

Extinction Coeff. Oxidized 28920.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0187873 VERIFIED: NO

Provenance & Taxonomy

OrganismOreochromis niloticus (Not founde tilapia) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria