Peptide Database

Peptide NameT-256

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Therapeutic / Biomedical activity ▸ Protective bioactivity ▸ Cell protection ▸ Cytoprotection

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC171H283N47O53

DescriptionStandard

        YLHRIDLGPPISLERLDVGTNLGNAIAKLEDAKEL
    

Molecular Weight3845.36 Da

Isoelectric Point (pI)4.95

Net Charge (pH 7.0)-2.14

Net Charge (pH 7.4) -2.41

Charge Density (pH 7.0) -0.0613

GRAVY Index-0.16

Hydrophobic Moment 0.54

Boman Index0.04

Instability Index6.72

Aliphatic Index 128.29

Aromaticity 0.0286

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1610.33

LogP -13.19

H-bond Donors 54.0

H-bond Acceptors 52.0

Rotatable Bonds 129.0

Heavy Atoms 271.0

Ring Count 4.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0376652 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiviral Cytotoxic Anticancer

TargetNo significant cytotoxic against HEp2 cells

Activity100 μM

MethodCC50

RECORD: Rec_0387056 VERIFIED: YES