Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length420 amino acids

Chemical FormulaC2092H3290N510O613S16

DescriptionStandard

        VLLKQKAASYRVSQMMAVWIQNKLKSTEIPEVRGGVDIGIGTVEYVISNMQVVQCSMSGPSMEFEKGIGVSVEVSQLSLAITGSWATQFGIIHDGGSVDLAVYNIKIKTLLGLGDEAGRLSITTISCSDDVGGVHIQFHGGICPAIQQAISELEKNLQEIPVNIPVDQYIYLSILLTSSPAVTDRSFELDFKGEFYSISSPSEPPFSASAFDVKYAENYMLSLAASEFLVNSAAYAYLSSEVLQINITDNMIPKSFPIHLNTSQFSAFIPQLRTLYPNMEMQVLLYASKTPLFSFSSGVIDIHVPVAAKFSVVKPDGMLVPLFRLDVVMTVGSSEIGDFKDPLGIVLFIIIIILLCIVDYLKTGFLLPTLQDFSLINSKLLIKNGFVVIFSDVEDSWTVSMKTKVQTSPNNHFNGVNLHA
    

Molecular Weight45906.59 Da

Isoelectric Point (pI)4.97

Net Charge (pH 7.0)-12.65

Net Charge (pH 7.4) -13.37

Charge Density (pH 7.0) -0.0301

GRAVY Index0.35

Hydrophobic Moment 0.62

Boman Index0.23

Instability Index35.51

Aliphatic Index 109.24

Aromaticity 0.0929

Extinction Coeff. Reduced 35870.00

Extinction Coeff. Oxidized 36120.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0394913 VERIFIED: NO

Provenance & Taxonomy

OrganismSinocyclocheilus rhinocerous [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria