Peptide Database

Peptide NameTemporin-FL

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC72H116N14O16

DescriptionStandard

        FIPLVSGLFSKLL
    

Molecular Weight1433.78 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0584

GRAVY Index1.69

Hydrophobic Moment 0.40

Boman Index0.60

Instability Index0.48

Aliphatic Index 172.31

Aromaticity 0.1538

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 470.21

LogP -0.16

H-bond Donors 16.0

H-bond Acceptors 17.0

Rotatable Bonds 45.0

Heavy Atoms 102.0

Ring Count 3.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0423797 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax nigromaculatus [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

Targetmethicillin-resistant Staphylococcus aureus NCTC 12493

Activity32 μM

MethodMIC

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