Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC445H701N129O141S8

DescriptionStandard

        MRTHALLAVLVLLALQAQNGSLPENAEEAPGQEQSGEEDQDKTIFFIMTETSALQDEHLGRGWICNCREGVCPLPEHNSGVCTIGIRWHTLCCH
    

Molecular Weight10370.63 Da

Isoelectric Point (pI)4.84

Net Charge (pH 7.0)-8.09

Net Charge (pH 7.4) -8.67

Charge Density (pH 7.0) -0.0861

GRAVY Index-0.20

Hydrophobic Moment 0.53

Boman Index0.06

Instability Index63.08

Aliphatic Index 86.17

Aromaticity 0.0426

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4301.16

LogP -45.49

H-bond Donors 150.0

H-bond Acceptors 146.0

Rotatable Bonds 341.0

Heavy Atoms 723.0

Ring Count 15.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0340829 VERIFIED: NO

Provenance & Taxonomy

OrganismCastor canadensis [Animal]

FamilyDefensin

Tax ID51338

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal