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MYP_161613
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Basic Information
[K]3 -VmCT1-NH2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C76H115N17O16
Standard
Sequence
FLKALWNVAKSVF
Physicochemical Analysis
1522.83 Da
10.00
1.76
1.55
0.1352
0.94
0.62
0.37
30.41
120.00
0.2308
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
543.67
-1.00
19.0
18.0
48.0
109.0
4.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0239185 VERIFIED: YES
Provenance & Taxonomy
Vaejovis mexicanus smithi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Aspergillus niger
12.5
MIC
PMID27912176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27912176/
RECORD: Rec_0265109 VERIFIED: YES
Provenance & Taxonomy
Vaejovis mexicanus smithi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Cladosporium herbarum ATCC 26362
25
MIC
PMID27912176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27912176/
RECORD: Rec_0266013 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis (ATCC 12228)
3.12 μM
MIC
PaperNovel designed VmCT1 analogs with increased antimicrobial activity. Eur J Med Chem. 2017 Jan 27;126:456-463. doi: 10.1016/j.ejmech.2016.11.040. PMID: 27912176. PMID27912176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27912176/
RECORD: Rec_0275558 VERIFIED: YES
Provenance & Taxonomy
Vaejovis mexicanus smithi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli SBS 363
1.56
MIC
PMID27912176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27912176/
RECORD: Rec_0280959 VERIFIED: YES
Provenance & Taxonomy
Vaejovis mexicanus smithi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 29213
3.12
MIC
PMID27912176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27912176/
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