MYP_161594
Piscidin-1 (Pis-1; Piscidin 1; fish, chordates, animals)
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Antimicrobial
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Antifungal
Antiviral
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Antiviral mechanism
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Immunology
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Innate immune defense
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Host defense peptide
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Host defense activity
Membrane / Ion-channel modulation
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Sodium channel modulation
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Sodium channel inhibitor
cross
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Venom / Toxin
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General toxin
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Toxic
Standard
22 amino acids
C122H187N37O25
Standard
FFHHIFRGIVHVGKTIHRLVTG
2572.02 Da
12.00
3.11
2.70
0.1413
0.45
0.73
0.24
8.11
110.45
0.1364
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
979.42
-5.37
36.0
32.0
82.0
184.0
7.0
21.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0151386
VERIFIED: YES
Provenance & Taxonomy
Morone saxatilis [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Antifungal
oxytoca
5-10 μM
MIC
RECORD: Rec_0164027
VERIFIED: YES
Provenance & Taxonomy
Lates calcarifer [Animal]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Staphylococcus aureus
2.34 μg/mL
MIC
RECORD: Rec_0168657
VERIFIED: YES
Provenance & Taxonomy
Morone saxatilis [Animal]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
allo-residue reported
Bio-Activity Profile
Antimicrobial
Antifungal
Anticancer
fungi: Candida albicans
>125 μg/mL
MIC
RECORD: Rec_0177117
VERIFIED: YES
Provenance & Taxonomy
Morone saxatilis [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Antifungal
Streptococcus iniae KST740 ak
1.25-2.5 μM
MIC
RECORD: Rec_0180107
VERIFIED: YES
Provenance & Taxonomy
Lates calcarifer [Animal]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Pseudomonas aeruginosa
75 μg/mL
MIC
Showing 5 records on this page · Page 8 of 19