‹ ›
MYP_161594
← PREVIOUS NEXT → BACK
Basic Information
Piscidin-1 (Pis-1; Piscidin 1; fish, chordates, animals)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor cross
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
22 amino acids
C122H187N37O25
Standard
Sequence
FFHHIFRGIVHVGKTIHRLVTG
Physicochemical Analysis
2572.02 Da
12.00
3.11
2.70
0.1413
0.45
0.73
0.24
8.11
110.45
0.1364
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
979.42
-5.37
36.0
32.0
82.0
184.0
7.0
21.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0214971 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Piscidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
10 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/11713517/ PMID11713517 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11713517/
RECORD: Rec_0219384 VERIFIED: YES
Provenance & Taxonomy
Lates calcarifer [Animal]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Candida glabrata
150 μg/mL
MIC
PMID30365554 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30365554/
RECORD: Rec_0222076 VERIFIED: YES
Provenance & Taxonomy
Lates calcarifer [Animal]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Candida albicans
9.37 μg/mL
MIC
PMID30365554 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30365554/
RECORD: Rec_0229108 VERIFIED: YES
Provenance & Taxonomy
Morone saxatilis [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
arizonae
10-20 μM
MIC
PMID11713517 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11713517/
RECORD: Rec_0233723 VERIFIED: YES
Provenance & Taxonomy
Morone saxatilis [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Vibrio Cholera
2.5-5 μM
MIC
PMID11713517 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11713517/
FIRST PREV 1 ... 10 11 12 13 14 ... 19 NEXT LAST
Showing 5 records on this page · Page 12 of 19