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MYP_161561
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Basic Information
ChBac3.4 (1-13, 15-26)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
25 amino acids
C160H240N46O27
Standard
Sequence
RFRLPFRRPPIRIPPPFYPPFRRFL
Physicochemical Analysis
3239.91 Da
12.00
6.76
6.55
0.2704
-0.60
0.62
-0.23
141.58
62.40
0.2400
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1144.93
-2.73
40.0
34.0
89.0
233.0
14.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0333833 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes: <5% Hemolysis=64 μM
PMID33194795 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33194795/
RECORD: Rec_0373257 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human PBMC (50% Cytotoxicity at 34.7+-7.3 microM
7.3 μM
Hemolysis
PMID33194795 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33194795/
RECORD: Rec_0387346 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
K562
25±3.5 μM
IC50
PMID33194795 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33194795/
RECORD: Rec_0390272 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ML-35p
4 μM
MIC
PMID33194795 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33194795/
RECORD: Rec_0402726 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 33591
16 μM
MIC
PMID33194795 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33194795/
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