Peptide Database

Peptide NameSLAY-screened peptide P1570

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC86H130N30O20

DescriptionStandard

        RWTSHAHRRYIPINP
    

Molecular Weight1904.14 Da

Isoelectric Point (pI)11.71

Net Charge (pH 7.0)2.93

Net Charge (pH 7.4) 2.63

Charge Density (pH 7.0) 0.1956

GRAVY Index-1.30

Hydrophobic Moment 0.57

Boman Index-0.31

Instability Index61.16

Aliphatic Index 58.67

Aromaticity 0.1333

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 815.77

LogP -7.05

H-bond Donors 30.0

H-bond Acceptors 25.0

Rotatable Bonds 55.0

Heavy Atoms 136.0

Ring Count 7.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0114863 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/