Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length519 amino acids

Chemical FormulaC2512H3988N670O753S21

DescriptionStandard

        MTSSVFPLFFWFFLSSSLAVFQHSGVKLRITDAAQDVLKEVVMAFLKELLNKPWDDISILDKKYAKYDISGLTFSCLSVSKDEIDLTFRDNSGVHFEVSDLAFTAAFKRKAKVGRINPDRGRSSIAGRGLSTTIEVNLNRDPQGHLKVEMGNCEFKADDILIVSHGKMGDVVDLFKTLIKKNIQEQICPSIKNFIPQVNSMSDQLTMRMNLPSELTSKLNVPGGQEIIIDYSVSGDVRVSANSLDIPFRGFVSTPGSNVDPDSIRKGEESVFTQTDQMAYVGISEFFLNSATTSLHRAGAMSKTDQVTQPILWGFLKFLQVFTHPFDLMNPMSSEVVVVEVPEISITRDKGVILKVPKVSGKVSAGQDVLSMEASCTVALKVAVEENYLILPSDDVDCTIATSSMIKDIMVKPLNWFLSSKVKTFLRGLFDKGLHIPLPEGMGFTQGNIVYQNGYLVVGGSLRLAPSGGEKVVELVMSNINTGGAAGGGAQQPAGGAQQPAGGAQHLAGGAQQPAGHHH
    

Molecular Weight56295.94 Da

Isoelectric Point (pI)6.15

Net Charge (pH 7.0)-4.53

Net Charge (pH 7.4) -5.50

Charge Density (pH 7.0) -0.0087

GRAVY Index-0.01

Hydrophobic Moment 0.73

Boman Index0.10

Instability Index36.90

Aliphatic Index 91.60

Aromaticity 0.0751

Extinction Coeff. Reduced 32430.00

Extinction Coeff. Oxidized 32680.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0269856 VERIFIED: NO

Provenance & Taxonomy

OrganismDicentrarchus labrax [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence