Peptide Database

Peptide NameSLAY-screened peptide P5610

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC106H171N27O23S3

DescriptionStandard

        PALLKFFYIIASCMRAALRC
    

Molecular Weight2287.85 Da

Isoelectric Point (pI)9.53

Net Charge (pH 7.0)2.94

Net Charge (pH 7.4) 2.85

Charge Density (pH 7.0) 0.1468

GRAVY Index1.18

Hydrophobic Moment 0.65

Boman Index0.28

Instability Index69.65

Aliphatic Index 117.50

Aromaticity 0.1500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 792.51

LogP -2.96

H-bond Donors 32.0

H-bond Acceptors 29.0

Rotatable Bonds 73.0

Heavy Atoms 159.0

Ring Count 4.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0388238 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/