Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC541H879N147O164S3

DescriptionStandard

        PDLTGHEKFGLGNVKYSISRIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRGTVHISKVFVTAILSTPLDNADPTSIALTSCRTTPGDVDIKLNGKT
    

Molecular Weight12162.85 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)2.22

Net Charge (pH 7.4) 1.97

Charge Density (pH 7.0) 0.0194

GRAVY Index0.07

Hydrophobic Moment 0.54

Boman Index0.13

Instability Index16.59

Aliphatic Index 100.88

Aromaticity 0.0526

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4941.03

LogP -53.97

H-bond Donors 175.0

H-bond Acceptors 172.0

Rotatable Bonds 399.0

Heavy Atoms 855.0

Ring Count 17.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0218861 VERIFIED: NO

Provenance & Taxonomy

OrganismAgelaius phoeniceus (Red-winged blackbird) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria