Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC467H753N135O139S10

DescriptionStandard

        MKAFSIAVAVTLVLAFVSVLEGATVPLGGQVEEVEEVKRVEEVEESINTPAAERQDLLAGYWMTAGHSRQKRQSHLALCRWCCNCCRNQKGCGICCKF
    

Molecular Weight10803.45 Da

Isoelectric Point (pI)6.70

Net Charge (pH 7.0)-0.38

Net Charge (pH 7.4) -0.84

Charge Density (pH 7.0) -0.0039

GRAVY Index0.05

Hydrophobic Moment 0.67

Boman Index0.04

Instability Index52.17

Aliphatic Index 86.53

Aromaticity 0.0612

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4416.20

LogP -44.44

H-bond Donors 161.0

H-bond Acceptors 151.0

Rotatable Bonds 362.0

Heavy Atoms 751.0

Ring Count 12.0

Amide Bonds 105.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0052742 VERIFIED: NO

Provenance & Taxonomy

OrganismGadus morhua [Animal]

FamilyHepcidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0412720 VERIFIED: NO