Peptide Database

Peptide NameDefensin; beta 4A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length59 amino acids

Chemical FormulaC300H467N87O75S7

DescriptionStandard

        MKIQVSWGPLPAEGLSGRVLFPLSCIGSSGFCFPFRCPHNREEIGRCFFPIQKCCRRQK
    

Molecular Weight6716.91 Da

Isoelectric Point (pI)9.42

Net Charge (pH 7.0)5.53

Net Charge (pH 7.4) 5.17

Charge Density (pH 7.0) 0.0938

GRAVY Index-0.11

Hydrophobic Moment 0.63

Boman Index-0.00

Instability Index62.77

Aliphatic Index 64.41

Aromaticity 0.1186

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2577.72

LogP -23.28

H-bond Donors 95.0

H-bond Acceptors 89.0

Rotatable Bonds 215.0

Heavy Atoms 469.0

Ring Count 15.0

Amide Bonds 62.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0338473 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal