Peptide Database

Peptide Nameflp-18 FMRFamide-related peptide 1

Function Ontology

Developmental biology ▸ Molting regulation

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Sleep regulation

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC83H126N20O23

DescriptionStandard

        SYFDEKKSVPGVLRF
    

Molecular Weight1772.01 Da

Isoelectric Point (pI)8.22

Net Charge (pH 7.0)0.46

Net Charge (pH 7.4) 0.25

Charge Density (pH 7.0) 0.0307

GRAVY Index-0.43

Hydrophobic Moment 0.49

Boman Index-0.07

Instability Index43.24

Aliphatic Index 64.67

Aromaticity 0.2000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 711.16

LogP -5.04

H-bond Donors 25.0

H-bond Acceptors 24.0

Rotatable Bonds 57.0

Heavy Atoms 126.0

Ring Count 4.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013926 VERIFIED: NO

Provenance & Taxonomy

OrganismCaenorhabditis elegans [Animal]

Tax ID6239

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0272441 VERIFIED: YES

Provenance & Taxonomy

OrganismCaenorhabditis elegans [Animal]

FamilyFMRFamide related peptide

Tax ID6239

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0379343 VERIFIED: YES

Provenance & Taxonomy

OrganismCaenorhabditis elegans [Animal]

FamilyFMRFamide-related peptide

Tax ID6239

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Myotropic Receptor modulation Immunomodulatory Sleep regulation Wake regulation Molting regulator

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0379535 VERIFIED: YES

Provenance & Taxonomy

OrganismCaenorhabditis elegans [Animal]

FamilyFMRFamide-related peptide

Tax ID6239

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Myotropic Receptor modulation Immunomodulatory Sleep regulation Wake regulation Molting regulator

Targetcoupled receptor

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour