Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC356H577N109O99S8

DescriptionStandard

        MRTSVLLFALLFFMSQVLPVRGRFKEICERPNGSCRNNCISTEVYVGRCLNGNPCCLPLGNQPRIRGTVPQDH
    

Molecular Weight8224.58 Da

Isoelectric Point (pI)9.21

Net Charge (pH 7.0)4.54

Net Charge (pH 7.4) 4.17

Charge Density (pH 7.0) 0.0621

GRAVY Index-0.09

Hydrophobic Moment 0.46

Boman Index-0.03

Instability Index36.20

Aliphatic Index 83.97

Aromaticity 0.0685

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3354.53

LogP -35.97

H-bond Donors 121.0

H-bond Acceptors 113.0

Rotatable Bonds 266.0

Heavy Atoms 572.0

Ring Count 12.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0189284 VERIFIED: NO

Provenance & Taxonomy

OrganismSpermophilus dauricus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence