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MYP_161299
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Basic Information
Beta-defensin 129
Antimicrobial
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
183 amino acids
C895H1457N241O268S13
Standard
Sequence
MKLLFPIFASLMLQYQVNTEFIGLRRCLMGLGRCRDHCNVDEKEIQKCKMKKCCVGPKVVKLIKNYLQYGTPNVLNEDVQEMLKPAKNSSAVIQRKHILSVLPQIKSTSFFANTNFVIIPNATPMNSATISTMTPGQITYTATSTKSNTKESRDSATASPPPAPPPPNILPTPSLELEEAEEQ
Physicochemical Analysis
20298.44 Da
9.04
5.63
5.18
0.0308
-0.29
0.72
-0.00
45.11
81.53
0.0546
5960.00
6335.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
8161.13
-102.30
277.0
289.0
670.0
1417.0
29.0
203.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0035770 VERIFIED: NO
Provenance & Taxonomy
Pan troglodytes [Animal]
Defensin
9598
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal
Qualitative functional evidence
PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q30KK0/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0374501 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Beta-defensin; Defensin
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Non-hemolytic
PMID12600824;12620395;12975309;11780052;15489334;11854508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12600824/