Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC251H402N66O81S4

DescriptionStandard

        MEKETTIIESIQEVSLEELDQIIGARKNGVFKTISHECHLNTWAFLATCCS
    

Molecular Weight5768.53 Da

Isoelectric Point (pI)4.86

Net Charge (pH 7.0)-4.34

Net Charge (pH 7.4) -4.71

Charge Density (pH 7.0) -0.0850

GRAVY Index-0.04

Hydrophobic Moment 0.49

Boman Index0.08

Instability Index32.25

Aliphatic Index 93.73

Aromaticity 0.0588

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2384.26

LogP -23.25

H-bond Donors 85.0

H-bond Acceptors 83.0

Rotatable Bonds 197.0

Heavy Atoms 402.0

Ring Count 6.0

Amide Bonds 54.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0129852 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus macedonicus [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria