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MYP_161260
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Basic Information
Medusin-PH
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
18 amino acids
C83H149N19O22S
Standard
Sequence
LLGMIPVAISAISALSKL
Physicochemical Analysis
1797.25 Da
8.75
0.76
0.55
0.0422
1.77
0.40
0.58
13.83
184.44
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
635.94
-3.33
22.0
24.0
59.0
125.0
1.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0203609 VERIFIED: YES
Provenance & Taxonomy
Agalychnis callidryas [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Candida albicans
PMID23415652 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23415652/
RECORD: Rec_0224376 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
8395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Enterococcus faecalis ATCC 29212
100 μM
MIC
PaperMedusins: A new class of antimicrobial peptides from the skin secretions of phyllomedusine frogs.
RECORD: Rec_0252255 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa hypochondrialis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
128 μg/mL
MIC
RECORD: Rec_0355126 VERIFIED: YES
Provenance & Taxonomy
Amphibia [Animal]
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID23390641 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23390641/
RECORD: Rec_0367067 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
8395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Candida albicans
128 μg/mL
MIC
PaperMedusins: A new class of antimicrobial peptides from the skin secretions of phyllomedusine frogs.
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