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MYP_161256
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Basic Information
Lynronne-3
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
20 amino acids
C119H186N42O26S
Standard
Sequence
NRFTARFRRTPWRLCLQFRQ
Physicochemical Analysis
2653.08 Da
12.00
5.75
5.53
0.2875
-1.05
0.66
-0.51
68.49
44.00
0.2000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1164.35
-10.64
45.0
33.0
85.0
188.0
6.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0157768 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Campylobacter jejuni
64-128 μg/mL
MIC
PMID29214045 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29214045/
RECORD: Rec_0160146 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
128 μg/mL
MIC
PMID29214045 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29214045/
RECORD: Rec_0180112 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Toxicity
it showed poor cytotoxicity to multiple cell lines
>589 μg/mL
CC50
PaperThe rumen microbiome: an underexplored resource for novel antimicrobial discovery PMID29214045 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29214045/
RECORD: Rec_0197627 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human hepatocellular carcinoma HepG2
24.4 μg/mL
IC50
PMID29214045 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29214045/
RECORD: Rec_0237713 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii Q12-0809
16 μg/mL
MIC
PMID29214045 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29214045/
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