Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC487H778N140O141S11

DescriptionStandard

        MPLLTTNCRKSFEKLYSERFNSSTIFVKVKYSTKKNNPARSKEDYVIFNWREACIKLSGRCKNQCGEKEFKMAYCARPTTLCCMRQCDHIEININ
    

Molecular Weight11202.96 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)8.52

Net Charge (pH 7.4) 8.10

Charge Density (pH 7.0) 0.0896

GRAVY Index-0.63

Hydrophobic Moment 0.51

Boman Index-0.19

Instability Index49.02

Aliphatic Index 58.53

Aromaticity 0.1053

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4646.85

LogP -48.27

H-bond Donors 171.0

H-bond Acceptors 162.0

Rotatable Bonds 382.0

Heavy Atoms 779.0

Ring Count 15.0

Amide Bonds 104.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0226721 VERIFIED: NO

Provenance & Taxonomy

OrganismNeogale vison [Animal]

FamilyDefensin

Tax ID452646

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal