Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC181H276N56O42S2

DescriptionStandard

        WFQRIPLGWFHCTYQKGKQHCRLRIRQKVEE
    

Molecular Weight3972.61 Da

Isoelectric Point (pI)10.05

Net Charge (pH 7.0)4.92

Net Charge (pH 7.4) 4.58

Charge Density (pH 7.0) 0.1588

GRAVY Index-1.03

Hydrophobic Moment 0.44

Boman Index-0.27

Instability Index45.60

Aliphatic Index 59.68

Aromaticity 0.1613

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1629.55

LogP -11.16

H-bond Donors 60.0

H-bond Acceptors 51.0

Rotatable Bonds 132.0

Heavy Atoms 281.0

Ring Count 10.0

Amide Bonds 34.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0182524 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

RECORD: Rec_0390342 VERIFIED: YES

Provenance & Taxonomy

OrganismZaire ebolavirus [Virus]

FamilyVirus-derived peptide

Tax ID186538;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Entry inhibitor

TargetEbola virus (Virus entry); Vero E6

MethodFlow cytometry

PaperEbolavirus delta-peptide immunoadhesins inhibit marburgvirus and ebolavirus cell entry. | Radoshitzky SR, Warfield KL, Chi X, Dong L, Kota K, Bradfute SB, Gearhart JD, Retterer C, Kranzusch PJ, Misasi JN, Hogenbirk MA, Wahl-Jensen V, Volchkov VE, Cunningham JM, Jahrling PB, Aman MJ, Bavari S, Farzan M, Kuhn JH. | J Virol. 2011 | PMID:21697477 PMID21697477 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21697477/