Peptide Database

Peptide Name[D-Ala2,F5,Phe4]dynorphin-(1-13)-NH2

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Neurological / Signaling ▸ Neuropeptide activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC76H128N24O15

DescriptionStandard

        YAGFLRRIRPKLK
    

Molecular Weight1617.98 Da

Isoelectric Point (pI)11.73

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.55

Charge Density (pH 7.0) 0.3659

GRAVY Index-0.61

Hydrophobic Moment 0.62

Boman Index-0.34

Instability Index88.08

Aliphatic Index 97.69

Aromaticity 0.1538

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 661.70

LogP -3.25

H-bond Donors 25.0

H-bond Acceptors 20.0

Rotatable Bonds 54.0

Heavy Atoms 115.0

Ring Count 3.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0418524 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Receptor agonist Opioid Analgesic Neuropeptide activity

Targetκ receptor (Mouse)