Peptide Database

Peptide NameBatifiban

Function Ontology

Antiplatelet GPIIb IIIa antagonist

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC28H50N8O9S

DescriptionStandard

        NAMINI
    

Molecular Weight674.81 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0400

GRAVY Index0.95

Hydrophobic Moment 0.41

Boman Index0.41

Instability Index81.57

Aliphatic Index 146.67

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 295.00

LogP -2.56

H-bond Donors 9.0

H-bond Acceptors 10.0

Rotatable Bonds 22.0

Heavy Atoms 46.0

Ring Count 0.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0149195 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermNone

Disulfide1-6

Other ModsComposite modified token aminoiminomethyl; Composite modified token mercapto; Composite modified token oxopropyl; Composite modified token trypotophyl; Composite modified token prolyl; Composite modified token disulfide

Bio-Activity Profile

Function

Antiplatelet GPIIb IIIa antagonist

MethodHPLC, MS-MS

Half-LifeHuman blood plasma (Women) (Intravenous bolus followed by a continuous infusion of batifiban injection), in vivo; 11232 s