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MYP_161199
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Basic Information
C-Type natriuretic peptide CNP-22
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
22 amino acids
C93H159N27O28S3
Standard
Sequence
GLSKGCFGLKLDRIGSMSGLGC
Physicochemical Analysis
2199.62 Da
8.90
1.74
1.50
0.0791
0.40
0.45
0.18
14.51
88.64
0.0455
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
886.35
-10.57
34.0
33.0
77.0
151.0
1.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0211439 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
CNP
9940
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-22
Bio-Activity Profile
Hormone Endocrine Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation
Experimental: 4.3 minutes; /258 seconds; Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for CNP-22 (Ovis aries): PMID 10219521##21459096 PMID10219521;21459096 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10219521/
RECORD: Rec_0228462 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
CNP
10116
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-22
Bio-Activity Profile
Hormone Endocrine Cardiovascular Metabolic regulation Physiological regulation Reproductive regulator Growth regulation Development regulation Receptor modulation ACE inhibitory
Experimental: 4.3 minutes; /258 seconds; Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for CNP-22 (Rattus norvegicus): PMID 21459096 PMID21459096 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21459096/
RECORD: Rec_0234529 VERIFIED: NO
Provenance & Taxonomy
Sus scrofa [Animal]; Bos taurus [Animal]; Homo sapiens [Animal]; Mus musculus [Animal]; Notomys alexis [Animal]; Rattus norvegicus [Animal]; Ovis aries [Animal]
9823, 9913, 9606, 10090, 10116, 9940
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-22
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0289183 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Natriuretic peptide
10116
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-22
Bio-Activity Profile
Hormone Cardiovascular
PMID2139780 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2139780/
RECORD: Rec_0290560 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
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