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MYP_161199
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Basic Information
C-Type natriuretic peptide CNP-22
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
22 amino acids
C93H159N27O28S3
Standard
Sequence
GLSKGCFGLKLDRIGSMSGLGC
Physicochemical Analysis
2199.62 Da
8.90
1.74
1.50
0.0791
0.40
0.45
0.18
14.51
88.64
0.0455
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
886.35
-10.57
34.0
33.0
77.0
151.0
1.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011908 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]; Polypterus endlicheri [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
RECORD: Rec_0032249 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Natriuretic peptide
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
6-22
Bio-Activity Profile
Natriuretic
Competitive Radioimmunoassay
Rat plasma (Subcutaneous), in vivo; 468 s
RECORD: Rec_0048562 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
CNP
9913
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-22
Bio-Activity Profile
Hormone Endocrine Cardiovascular Metabolic regulation Physiological regulation Reproductive regulator Growth regulation Development regulation Receptor modulation ACE inhibitory
Experimental: 4.3 minutes; /258 seconds; Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for CNP-22 (Bos taurus): PMID 21459096 PMID21459096 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21459096/
RECORD: Rec_0081330 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Natriuretic peptide
9823
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-22
Bio-Activity Profile
Hormone Cardiovascular
PMID2139780 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2139780/
RECORD: Rec_0111031 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Natriuretic peptide
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-22
Bio-Activity Profile
Hormone Cardiovascular
PMID2139780 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2139780/
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