Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length121 amino acids

Chemical FormulaC603H964N168O176S8

DescriptionStandard

        MRLLLLALPILALLPQVIPAYGGEKKCWNKSGHCRKQCKDEETMKGKCTNHRVCCVPDSKRPWQVPETPPTSSYDLTSVPFDVILTLTFTTRHFEVKSDTVTAEPSEVVHATETSRPKVHH
    

Molecular Weight13639.65 Da

Isoelectric Point (pI)8.57

Net Charge (pH 7.0)2.98

Net Charge (pH 7.4) 2.34

Charge Density (pH 7.0) 0.0246

GRAVY Index-0.41

Hydrophobic Moment 0.40

Boman Index-0.05

Instability Index52.84

Aliphatic Index 75.62

Aromaticity 0.0579

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5459.53

LogP -53.82

H-bond Donors 194.0

H-bond Acceptors 193.0

Rotatable Bonds 439.0

Heavy Atoms 955.0

Ring Count 26.0

Amide Bonds 125.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0148776 VERIFIED: NO

Provenance & Taxonomy

OrganismProlemur simus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence