Peptide Database

Peptide NameCec4-1(Cec4 amino acid replacement peptide)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC190H329N63O55

DescriptionStandard

        GWRKKIGKKIERVGQNTRDATIQAIGVAQQAANVAATLKGK
    

Molecular Weight4376.03 Da

Isoelectric Point (pI)11.17

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.54

Charge Density (pH 7.0) 0.1648

GRAVY Index-0.56

Hydrophobic Moment 0.88

Boman Index-0.15

Instability Index11.61

Aliphatic Index 85.85

Aromaticity 0.0244

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1978.76

LogP -23.13

H-bond Donors 69.0

H-bond Acceptors 62.0

Rotatable Bonds 156.0

Heavy Atoms 308.0

Ring Count 2.0

Amide Bonds 46.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0162448 VERIFIED: YES

Provenance & Taxonomy

OrganismMusca domestica [Animal]

Tax ID7370

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetAcinetobacter baumannii

Paper抗菌肽Cec4的结构改造及抗菌活性研究; Structural modification and antibacterial related activity study of antimicrobial peptide Cec4. [J].生物技术,2019,29(04):330-335. DOI:10.16519/j.cnki.1004-311x.2019.04.0056. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37237

RECORD: Rec_0405109 VERIFIED: YES