Peptide Database

Peptide NameCycloviolacin O16

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC118H183N33O38S6

DescriptionStandard

        GLPVCGETCFGGTCNTPGCSCTWPICTR
    

Molecular Weight2864.30 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0106

GRAVY Index0.24

Hydrophobic Moment 0.27

Boman Index0.20

Instability Index48.61

Aliphatic Index 38.21

Aromaticity 0.0714

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1102.11

LogP -15.64

H-bond Donors 44.0

H-bond Acceptors 44.0

Rotatable Bonds 82.0

Heavy Atoms 195.0

Ring Count 6.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0245468 VERIFIED: YES

Provenance & Taxonomy

OrganismOldenlandia affinis [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)