Peptide Database

Peptide NameNigrocin-2ISb

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC324H537N87O98S6

DescriptionStandard

        MFTLKKSMLLLFFLGTINLSLCQEERDAEEERRDEDNAKMEEIKRGILGTVFKAGKGIVCGLTGLC
    

Molecular Weight7411.64 Da

Isoelectric Point (pI)5.36

Net Charge (pH 7.0)-1.51

Net Charge (pH 7.4) -1.79

Charge Density (pH 7.0) -0.0229

GRAVY Index-0.05

Hydrophobic Moment 0.50

Boman Index0.01

Instability Index42.27

Aliphatic Index 96.06

Aromaticity 0.0606

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3019.49

LogP -25.94

H-bond Donors 108.0

H-bond Acceptors 103.0

Rotatable Bonds 264.0

Heavy Atoms 515.0

Ring Count 4.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0149183 VERIFIED: NO

Provenance & Taxonomy

OrganismOdorrana ishikawae [Animal]

FamilyNigrocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0214467 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana ishikawae [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-MRSA Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetBacillus subtilis (Gram-positive)

RECORD: Rec_0221165 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana ishikawae [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-MRSA Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0281141 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana ishikawae [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-MRSA Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0334593 VERIFIED: YES

Provenance & Taxonomy

OrganismOdorrana ishikawae [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-MRSA Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetCandida albicans