Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC383H607N103O107S9

DescriptionStandard

        MALIRKMFYFVFAVFFILAQQPSGSQAGLEFSQPFSSGEFAVCESCKLGRGKCRKECLESEKAVGSCRLNLLCCRSTI
    

Molecular Weight8655.13 Da

Isoelectric Point (pI)8.79

Net Charge (pH 7.0)3.44

Net Charge (pH 7.4) 3.10

Charge Density (pH 7.0) 0.0441

GRAVY Index0.26

Hydrophobic Moment 0.49

Boman Index0.08

Instability Index66.22

Aliphatic Index 77.56

Aromaticity 0.1154

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3387.82

LogP -32.92

H-bond Donors 126.0

H-bond Acceptors 120.0

Rotatable Bonds 292.0

Heavy Atoms 602.0

Ring Count 11.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0002307 VERIFIED: NO

Provenance & Taxonomy

OrganismSapajus apella (Brown-capped capuchin) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

RECORD: Rec_0217465 VERIFIED: NO

Provenance & Taxonomy

OrganismCebus imitator [Animal]

FamilyDefensin

Tax ID9516

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence