Peptide Database

Peptide NameFR-15 [F4P]

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC115H154N30O16

DescriptionStandard

        FRRPFKWFRRFFKFF
    

Molecular Weight2212.64 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.55

Charge Density (pH 7.0) 0.3839

GRAVY Index-0.58

Hydrophobic Moment 1.03

Boman Index-0.26

Instability Index91.35

Aliphatic Index 0.00

Aromaticity 0.5333

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 777.36

LogP 0.43

H-bond Donors 30.0

H-bond Acceptors 22.0

Rotatable Bonds 68.0

Heavy Atoms 161.0

Ring Count 10.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0403679 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetHuman hepatocellular carcinoma HepG2

Activity2.5 μM

MethodIC50

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