Peptide Database

Peptide NameTemporin-SHf (Temp-SHf) (Phe-rich antimicrobial peptide)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC236H367N65O78S

DescriptionStandard

        FLGTINLSLCEEERDADEEERRDEPDESNVEVKKRFFFLSRIFGK
    

Molecular Weight5394.89 Da

Isoelectric Point (pI)4.55

Net Charge (pH 7.0)-5.22

Net Charge (pH 7.4) -5.46

Charge Density (pH 7.0) -0.1161

GRAVY Index-0.92

Hydrophobic Moment 0.48

Boman Index-0.28

Instability Index63.59

Aliphatic Index 67.11

Aromaticity 0.1111

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2374.49

LogP -22.26

H-bond Donors 83.0

H-bond Acceptors 74.0

Rotatable Bonds 188.0

Heavy Atoms 380.0

Ring Count 6.0

Amide Bonds 46.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0170932 VERIFIED: NO

Provenance & Taxonomy

OrganismPelophylax saharicus [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-MRSA Cytolytic Hemolytic