Peptide Database

Peptide NamePleurain-A2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC355H586N94O107S6

DescriptionStandard

        MFTLKKTLLLLYFLGTISISLCKQERDADEDDGRKMTEEEVKRSIITMTKEAKLPQSWKQIACRLYNTC
    

Molecular Weight8075.41 Da

Isoelectric Point (pI)8.50

Net Charge (pH 7.0)1.48

Net Charge (pH 7.4) 1.19

Charge Density (pH 7.0) 0.0215

GRAVY Index-0.39

Hydrophobic Moment 0.56

Boman Index-0.11

Instability Index61.26

Aliphatic Index 87.68

Aromaticity 0.0725

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3313.23

LogP -28.87

H-bond Donors 120.0

H-bond Acceptors 115.0

Rotatable Bonds 283.0

Heavy Atoms 562.0

Ring Count 7.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0092912 VERIFIED: YES

Provenance & Taxonomy

OrganismNidirana pleuraden [Animal]

FamilyFrog skin active peptide (FSAP); Pleurain subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetHelicobacter pylori

RECORD: Rec_0096220 VERIFIED: YES

Provenance & Taxonomy

OrganismNidirana pleuraden [Animal]

FamilyFrog skin active peptide (FSAP); Pleurain subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetEscherichia coli

RECORD: Rec_0133613 VERIFIED: YES

Provenance & Taxonomy

OrganismNidirana pleuraden [Animal]

FamilyFrog skin active peptide (FSAP); Pleurain subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0401981 VERIFIED: YES

Provenance & Taxonomy

OrganismNidirana pleuraden [Animal]

FamilyFrog skin active peptide (FSAP); Pleurain subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetCandida albicans