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MYP_160979
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Basic Information
Pa-MAP, Antifreeze peptide analogue
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
26 amino acids
C90H149N29O34S
Standard
Sequence
HTASDAAAAAALTAANAAAAAAASMA
Physicochemical Analysis
2213.38 Da
5.08
-1.15
-1.41
-0.0443
0.89
0.23
0.37
11.46
80.38
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
980.81
-16.28
34.0
35.0
66.0
154.0
1.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0020365 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antifungal
Human colon adenocarcinoma Caco-2
60 μM
ED50
PMID27161201;23056574 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27161201/
RECORD: Rec_0080941 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antifungal
Murine macrophage cells RAW 264.7
PMID27161201;23056574 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27161201/
RECORD: Rec_0084627 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antifungal
Trichophyton mentagrophytes
115 μM
MIC
PMID27161201;23056574 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27161201/
RECORD: Rec_0112768 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antifungal
HSV-1
90 μM
ED50
PMID27161201;23056574 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27161201/
RECORD: Rec_0130298 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Antifungal
HSV-1[90-100% Inhibition = 200 microg/ml
PMID27161201;23056574 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27161201/
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