Peptide Database

Peptide NameLL-II/2 (Lasioglossin LL-II peptide derivative)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC85H150N22O17

DescriptionStandard

        VNWKKILAKIIKVAK
    

Molecular Weight1752.24 Da

Isoelectric Point (pI)10.60

Net Charge (pH 7.0)4.73

Net Charge (pH 7.4) 4.51

Charge Density (pH 7.0) 0.3153

GRAVY Index0.36

Hydrophobic Moment 0.70

Boman Index0.08

Instability Index-7.38

Aliphatic Index 156.00

Aromaticity 0.0667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 659.70

LogP -1.03

H-bond Donors 23.0

H-bond Acceptors 22.0

Rotatable Bonds 63.0

Heavy Atoms 124.0

Ring Count 2.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0414773 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity0.7 μM

MethodMIC

RECORD: Rec_0418802 VERIFIED: YES