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MYP_160957
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Basic Information
LL-II/2 (Lasioglossin LL-II peptide derivative)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
15 amino acids
C85H150N22O17
Standard
Sequence
VNWKKILAKIIKVAK
Physicochemical Analysis
1752.24 Da
10.60
4.73
4.51
0.3153
0.36
0.70
0.08
-7.38
156.00
0.0667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
659.70
-1.03
23.0
22.0
63.0
124.0
2.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0184211 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
4.3 μM
MIC
PaperLasioglossins: three novel antimicrobial peptides from the venom of the eusocial bee Lasioglossum laticeps (Hymenoptera: Halictidae). Chembiochem. 2009 Aug 17;10(12):2089-99. doi: 10.1002/cbic.200900133. PMID: 19591185. PMID19591185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19591185/
RECORD: Rec_0312058 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Rat red blood cells
66.5 μM
LC50
PMID19591185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19591185/
RECORD: Rec_0337394 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
rat red blood cells
PaperLasioglossins: three novel antimicrobial peptides from the venom of the eusocial bee Lasioglossum laticeps (Hymenoptera: Halictidae). Chembiochem. 2009 Aug 17;10(12):2089-99. doi: 10.1002/cbic.200900133. PMID: 19591185. PMID19591185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19591185/
RECORD: Rec_0359392 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperLasioglossins: three novel antimicrobial peptides from the venom of the eusocial bee Lasioglossum laticeps (Hymenoptera: Halictidae). Chembiochem. 2009 Aug 17;10(12):2089-99. doi: 10.1002/cbic.200900133. PMID: 19591185. PMID19591185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19591185/
RECORD: Rec_0393293 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
0.7 μM
MIC
PMID19591185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19591185/
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