Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length176 amino acids

Chemical FormulaC838H1337N251O250S13

DescriptionStandard

        MGNRAKLSAAMLALMAAGASAPTLMDQFLDEKEGNSLTAYRDGSQGIWTICRGATRIDGKPVTQGMKLTKAKCDQVNAIERDKALAWVDRNIHVPLTPPQKVGIASFCPYNIGPGKCFPSTFYQRINAGDRKGACEAIRWWIKDGGKDCRVRSNNCYGQVTRRDQESALTCWGIDQ
    

Molecular Weight19344.96 Da

Isoelectric Point (pI)9.19

Net Charge (pH 7.0)7.52

Net Charge (pH 7.4) 7.10

Charge Density (pH 7.0) 0.0427

GRAVY Index-0.45

Hydrophobic Moment 0.75

Boman Index-0.07

Instability Index31.26

Aliphatic Index 68.86

Aromaticity 0.0739

Extinction Coeff. Reduced 33460.00

Extinction Coeff. Oxidized 33960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8121.76

LogP -90.85

H-bond Donors 290.0

H-bond Acceptors 272.0

Rotatable Bonds 643.0

Heavy Atoms 1352.0

Ring Count 27.0

Amide Bonds 192.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0311633 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage ST846-OXA48phi9.1 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic