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MYP_160858
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Basic Information
Chrysophsin-2
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
25 amino acids
C136H211N47O26
Standard
Sequence
FFGWLIRGAIHAGKAIHGLIHRRRH
Physicochemical Analysis
2920.43 Da
12.00
5.11
4.70
0.2043
-0.02
0.60
0.06
73.47
105.60
0.1200
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1165.85
-6.85
44.0
35.0
95.0
209.0
8.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008204 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
1 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/12581207/ PMID12581207 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12581207/
RECORD: Rec_0010980 VERIFIED: YES
Provenance & Taxonomy
Chrysophrys major [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Lactococcus garvieae ATCC 49156
5 μM
MIC
PMID12581207 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12581207/
RECORD: Rec_0017916 VERIFIED: YES
Provenance & Taxonomy
Pagrus major [Animal]
Pleurocidin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Vibrio harveyi HUFP911 1 ATCC 14126
PMID12581207 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12581207/
RECORD: Rec_0020067 VERIFIED: YES
Provenance & Taxonomy
Red sea bream [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Vibriopenaeicida KHA
5 μM
MIC
PaperPurification and characterization of three isoforms of chrysophsin, a novel antimicrobial peptide in the gills of the red sea bream, Chrysophrys major.
RECORD: Rec_0051245 VERIFIED: YES
Provenance & Taxonomy
Pagrus major [Animal]
Pleurocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic
A. salmonicida (Gram-negative)
PMID12581207 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12581207/
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