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MYP_160839
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Basic Information
Mel(12-26, S6)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C79H134N26O20
Standard
Sequence
GLPALSSWIKRKRQQ
Physicochemical Analysis
1768.07 Da
12.00
3.76
3.55
0.2505
-0.96
0.54
-0.31
111.34
84.67
0.0667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
780.20
-7.49
28.0
24.0
60.0
125.0
3.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0050445 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
39 μg/mL
MIC
PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
RECORD: Rec_0084926 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
650 μg/mL
Paperhttps://pubmed.ncbi.nlm.nih.gov/14596922/ PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
RECORD: Rec_0089273 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
14.6 μg/mL
MIC
PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
RECORD: Rec_0265114 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human erythrocytes
650 μg/mL
Hemolysis
PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
RECORD: Rec_0325235 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 40.0%, E 0.0%, T 20.0%, C 40.0% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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