Peptide Database

Peptide NameDEFA5 isoform 1 (Defensin alpha 5)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC428H707N135O140S7

DescriptionStandard

        MRTLAILAAILLVALQAQAESLQERADEAATQKQSGEDNQDLAVSFAGNGLSTLRASDSQARSTCYCRIGLCAAIESYSGRCYINGRRYRLCCR
    

Molecular Weight10208.47 Da

Isoelectric Point (pI)8.28

Net Charge (pH 7.0)1.45

Net Charge (pH 7.4) 1.13

Charge Density (pH 7.0) 0.0155

GRAVY Index-0.14

Hydrophobic Moment 0.48

Boman Index-0.07

Instability Index49.14

Aliphatic Index 88.51

Aromaticity 0.0532

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4525.15

LogP -57.09

H-bond Donors 168.0

H-bond Acceptors 149.0

Rotatable Bonds 347.0

Heavy Atoms 710.0

Ring Count 5.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416460 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9601

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic