Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length133 amino acids

Chemical FormulaC702H1071N191O195S11

DescriptionStandard

        MAAPMLTFIICGLLTQMAKGWWELKCWKNDLGHCRRRCLDNERYIRLCKNKVSCCLPLRFSHEYTRRPPPAFMRPEDVTVDFSDWTPFPVSPNLSDTFPFNTNEPYETFPTTQEQHTSKIVEHTSQVYVIRAI
    

Molecular Weight15658.89 Da

Isoelectric Point (pI)8.19

Net Charge (pH 7.0)1.80

Net Charge (pH 7.4) 1.25

Charge Density (pH 7.0) 0.0135

GRAVY Index-0.43

Hydrophobic Moment 0.62

Boman Index-0.05

Instability Index53.02

Aliphatic Index 65.94

Aromaticity 0.1203

Extinction Coeff. Reduced 27960.00

Extinction Coeff. Oxidized 28335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6170.43

LogP -54.19

H-bond Donors 220.0

H-bond Acceptors 212.0

Rotatable Bonds 494.0

Heavy Atoms 1099.0

Ring Count 36.0

Amide Bonds 142.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0090024 VERIFIED: NO

Provenance & Taxonomy

OrganismDipodomys ordii [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic