Peptide Database

Peptide NameSLAY-screened peptide P3662

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC91H143N29O29S

DescriptionStandard

        LTRAPHAASHCFNTLNSLDA
    

Molecular Weight2139.35 Da

Isoelectric Point (pI)6.91

Net Charge (pH 7.0)-0.07

Net Charge (pH 7.4) -0.39

Charge Density (pH 7.0) -0.0037

GRAVY Index-0.10

Hydrophobic Moment 0.50

Boman Index0.05

Instability Index14.88

Aliphatic Index 78.50

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 931.09

LogP -12.33

H-bond Donors 33.0

H-bond Acceptors 32.0

Rotatable Bonds 65.0

Heavy Atoms 150.0

Ring Count 4.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0212532 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/