Peptide Database

Peptide NameLeptin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC709H1160N190O220S6

DescriptionStandard

        VPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQKVTGLDFIPGLHPILTLSKMDQTLAVYQQILTSMPSRNMIQISNDLENLRDLLHVLAFSKSCHLPWASGLETLDSLGGVLEASGYSTEVVALSRLQGSLQDMLWQLDLSPGC
    

Molecular Weight16058.33 Da

Isoelectric Point (pI)5.71

Net Charge (pH 7.0)-2.92

Net Charge (pH 7.4) -3.39

Charge Density (pH 7.0) -0.0200

GRAVY Index0.02

Hydrophobic Moment 0.66

Boman Index0.10

Instability Index44.16

Aliphatic Index 111.44

Aromaticity 0.0411

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6581.57

LogP -67.83

H-bond Donors 227.0

H-bond Acceptors 227.0

Rotatable Bonds 540.0

Heavy Atoms 1125.0

Ring Count 18.0

Amide Bonds 160.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0188633 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyLeptin

Tax ID9598

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic