Peptide Database

Peptide NameHINA_HORVU

Function Ontology

Antimicrobial

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length149 amino acids

Chemical FormulaC732H1121N203O205S14

DescriptionStandard

        MKALFLMGLLALVASAAFAQYGEVVGSYEGGAGGGGAQQCPLGTKLDSCRNYLLDRCTTMKDFPVTWRWWTWWKGGCEELLHDCCSQLSQMPPQCRCNIIQGSIQRDLGGFFGFQRDRTVKVIQAAKNLPPRCNQGPACNIPSTIGYYW
    

Molecular Weight16493.88 Da

Isoelectric Point (pI)8.56

Net Charge (pH 7.0)3.50

Net Charge (pH 7.4) 3.06

Charge Density (pH 7.0) 0.0235

GRAVY Index-0.14

Hydrophobic Moment 0.52

Boman Index0.08

Instability Index40.70

Aliphatic Index 71.41

Aromaticity 0.1141

Extinction Coeff. Reduced 40450.00

Extinction Coeff. Oxidized 41075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6521.35

LogP -63.44

H-bond Donors 234.0

H-bond Acceptors 224.0

Rotatable Bonds 530.0

Heavy Atoms 1154.0

Ring Count 32.0

Amide Bonds 164.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0058914 VERIFIED: YES

Provenance & Taxonomy

OrganismHordeum vulgare [Plant]

Tax ID4513

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond reported, sites not specified

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme

RECORD: Rec_0287816 VERIFIED: YES