Peptide Database

Peptide NameCathelicidin antimicrobial peptide [Cleaved into: Antibacterial peptide FALL-39 (FALL-39 peptide antibiotic); Antibacterial peptide LL-37]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length170 amino acids

Chemical FormulaC852H1389N247O250S7

DescriptionStandard

        MKTQRDSPSLGRWSLVLLLLGLVMPLAIVAQVLSYQEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCVGTVILNQARDSFDISCDKDNRRFALPGNFFRKAREKIGKEFKRIVQRIKDFLQHLVPRTEA
    

Molecular Weight19317.10 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)5.57

Net Charge (pH 7.4) 5.20

Charge Density (pH 7.0) 0.0328

GRAVY Index-0.41

Hydrophobic Moment 0.94

Boman Index-0.13

Instability Index42.65

Aliphatic Index 89.41

Aromaticity 0.0647

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8080.33

LogP -87.68

H-bond Donors 283.0

H-bond Acceptors 264.0

Rotatable Bonds 650.0

Heavy Atoms 1356.0

Ring Count 24.0

Amide Bonds 183.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0115603 VERIFIED: YES

Provenance & Taxonomy

OrganismNomascus gabriellae [other]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Antibiofilm Antifungal Anti-Candida Anti-Gram-negative Hemolytic

TargetBacillus megaterium

RECORD: Rec_0372269 VERIFIED: YES