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MYP_160490
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Basic Information
Signiferin 2.2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
15 amino acids
C76H128N18O17
Standard
Sequence
IIGHLIKTALGFLGL
Physicochemical Analysis
1565.94 Da
8.76
0.85
0.59
0.0564
1.62
0.45
0.65
3.67
188.67
0.0667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
545.65
-0.86
19.0
19.0
52.0
111.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0191495 VERIFIED: YES
Provenance & Taxonomy
Crinia signifera [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Lactococcus lactis
PMID15317042;16470724;18601958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15317042/
RECORD: Rec_0207076 VERIFIED: YES
Provenance & Taxonomy
Crinia signifera [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Staphylococcus aureus
PMID15317042;16470724;18601958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15317042/
RECORD: Rec_0221315 VERIFIED: YES
Provenance & Taxonomy
Crinia signifera [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Enterobacter cloacae
PMID15317042;16470724;18601958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15317042/
RECORD: Rec_0233822 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0248152 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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