Peptide Database

Peptide NameInsulin A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC95H157N29O33S4

DescriptionStandard

        GIVDQCCTNICSRNQLLTYCN
    

Molecular Weight2361.70 Da

Isoelectric Point (pI)5.81

Net Charge (pH 7.0)-0.28

Net Charge (pH 7.4) -0.54

Charge Density (pH 7.0) -0.0133

GRAVY Index0.07

Hydrophobic Moment 0.41

Boman Index0.01

Instability Index31.44

Aliphatic Index 88.10

Aromaticity 0.0476

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1040.89

LogP -14.12

H-bond Donors 39.0

H-bond Acceptors 37.0

Rotatable Bonds 77.0

Heavy Atoms 161.0

Ring Count 1.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0232803 VERIFIED: YES

Provenance & Taxonomy

OrganismProechimys guairae [Animal]

FamilyInsulin

Tax ID10163

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour