Peptide Database

Peptide NameDefensin alpha-3

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC157H237N49O37S6

DescriptionStandard

        ACYCRIPACLAGERRYGTCFYRRRVWAFCC
    

Molecular Weight3595.26 Da

Isoelectric Point (pI)9.18

Net Charge (pH 7.0)4.74

Net Charge (pH 7.4) 4.45

Charge Density (pH 7.0) 0.1579

GRAVY Index0.06

Hydrophobic Moment 0.60

Boman Index-0.11

Instability Index97.65

Aliphatic Index 49.00

Aromaticity 0.2000

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1403.84

LogP -11.49

H-bond Donors 60.0

H-bond Acceptors 48.0

Rotatable Bonds 109.0

Heavy Atoms 249.0

Ring Count 8.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0411911 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-29; 4-19; 9-30

Bio-Activity Profile

Function

Antimicrobial

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